TY - JOUR
T1 - Corynebacterium striatum
T2 - Jekyll or Hyde in the lungs
AU - Maria Fernandes, Anisha
AU - Suman, Ethel
AU - Acharya, Preetam R.
AU - Hegde, Atmananda S.
N1 - Publisher Copyright:
© 2024
PY - 2024
Y1 - 2024
N2 - A 50-year-old male patient, with Human immunodeficiency virus (HIV) and multiple co-morbidities was admitted with a fractured femur. He developed respiratory symptoms; good-quality sputum was sent for culture, which showed Gram-positive bacilli in palisades. The isolate was identified as Corynebacterium striatum (C. striatum) by Matrix-assisted laser desorption ionization time-of-flight mass spectrometry and was sensitive to Vancomycin, Linezolid, and Rifampicin. The respiratory symptoms worsened necessitating intubation. Endotracheal aspirate sent for culture and sensitivity yielded C. striatum and multi-drug resistant Acinetobacter baumannii. The patient deteriorated rapidly and succumbed to his illness. C. striatum is an opportunistic pathogen and should not be overlooked as a commensal when isolated from good-quality clinical specimens. It is an emerging pathogen in severe and often fatal pneumonia in immunocompromised patients. Recent reports of its outbreaks and multi-drug resistance are worrisome. Further investigation is required to develop effective infection control measures to prevent spread and outbreaks in health care settings.
AB - A 50-year-old male patient, with Human immunodeficiency virus (HIV) and multiple co-morbidities was admitted with a fractured femur. He developed respiratory symptoms; good-quality sputum was sent for culture, which showed Gram-positive bacilli in palisades. The isolate was identified as Corynebacterium striatum (C. striatum) by Matrix-assisted laser desorption ionization time-of-flight mass spectrometry and was sensitive to Vancomycin, Linezolid, and Rifampicin. The respiratory symptoms worsened necessitating intubation. Endotracheal aspirate sent for culture and sensitivity yielded C. striatum and multi-drug resistant Acinetobacter baumannii. The patient deteriorated rapidly and succumbed to his illness. C. striatum is an opportunistic pathogen and should not be overlooked as a commensal when isolated from good-quality clinical specimens. It is an emerging pathogen in severe and often fatal pneumonia in immunocompromised patients. Recent reports of its outbreaks and multi-drug resistance are worrisome. Further investigation is required to develop effective infection control measures to prevent spread and outbreaks in health care settings.
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U2 - 10.1016/j.mjafi.2024.07.003
DO - 10.1016/j.mjafi.2024.07.003
M3 - Article
AN - SCOPUS:85203279511
SN - 0377-1237
JO - Medical Journal Armed Forces India
JF - Medical Journal Armed Forces India
ER -