Coxsackie B1 infection associated with ventriculitis

Ventriculitis associated with acute enterovirus central nervous system infections is very rare. A case of a 7-week-old infant with coxsackie B1 meningitis and ventriculitis is presented. Cerebrospinal fluid analysis showed marked pleocytosis, hypoglycorrhachia and elevated protein simulating acute pyogenic meningitis. Magnetic resonance imaging of the brain revealed ventriculitis. The diagnosis of enterovirus infection was confirmed by positive cerebrospinal fluid polymerase chain reaction and culture for enterovirus. This case illustrates several of the unusual findings associated with enterovirus meningitis.