TY - CHAP
T1 - Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications
AU - Thakur, Goutam
AU - Rodrigues, Fiona Concy
AU - Singh, Krizma
PY - 2018/1/1
Y1 - 2018/1/1
N2 - A popular approach to attaining controlled drug delivery from polymer based systems involves the use of cross-linkers. In order to improve the properties of polymers specific to their applications, they can be modified by either physical cross-linkers (high pressure, irradiation) or chemical cross-linkers (glutaraldehyde, genipin). This chapter provides an insight into the different types and mechanisms of cross-linking. It reviews the existing drug delivery systems to understand the effects of cross-linking in them. The recent applications of cross-linked polymeric drug delivery and tissue engineering systems are also discussed.
AB - A popular approach to attaining controlled drug delivery from polymer based systems involves the use of cross-linkers. In order to improve the properties of polymers specific to their applications, they can be modified by either physical cross-linkers (high pressure, irradiation) or chemical cross-linkers (glutaraldehyde, genipin). This chapter provides an insight into the different types and mechanisms of cross-linking. It reviews the existing drug delivery systems to understand the effects of cross-linking in them. The recent applications of cross-linked polymeric drug delivery and tissue engineering systems are also discussed.
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U2 - 10.1007/978-981-13-0950-2_11
DO - 10.1007/978-981-13-0950-2_11
M3 - Chapter
C2 - 30357625
AN - SCOPUS:85055597236
T3 - Advances in Experimental Medicine and Biology
SP - 213
EP - 231
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -