Cytologic diagnosis of small cell anaplastic hepatoblastoma: A case report

Thoppil Reba Philipose, Ramadas Naik, Sharada Rai

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


Background: Small cell anaplastic hepatoblastoma (HB) is the least common subtype of HB. There are few articles in the literature describing the cytologic characteristics of this rare subtype. Case: A 5-year-old girl presented with a progressively enlarging abdominal mass. Ultrasound examination revealed the mass to be arising within the right lobe of the liver. Fine needle aspiration (FNA) of the mass revealed primitive cells with a high nuclear/cytoplasmic ratio and hyperchromatic, ovoid nuclei in poorly cohesive clusters as well as dispersed singly. These cells closely resembled those of small round cell tumors of childhood. Conclusion: The cytologic differential diagnosis of undifferentiated HB must include small round cell tumors of childhood. With knowledge of the typical cytomorphologic appearance of HB in association with clinical and radiologic information, one can offer a reliable preoperative diagnosis on FNA.

Original languageEnglish
Pages (from-to)205-207
Number of pages3
JournalActa Cytologica
Issue number2
Publication statusPublished - 01-01-2006

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology


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