Dendritic core-shell copper-nickel alloy@metal oxide for efficient non-enzymatic glucose detection

Huige Wei, Qizhou Xu, Ang Li, Tong Wan, Yan Huang, Dapeng Cui, Duo Pan, Binbin Dong, Renbo Wei, Nithesh Naik, Zhanhu Guo

Research output: Contribution to journalArticlepeer-review

33 Citations (SciVal)


A success has been achieved in the synthesis of dendritic core-shell copper-nickel alloy@metal oxide on nickel foam (Cu-Ni/NF) electrode for non-enzymatic glucose detection by going through a facile electrodeposition process followed by oxidation in NaOH solution. The direct electrodeposition approach facilitates the transfer of electrons in the binder-free electrode, and the dendritic structure promotes glucose diffusion while providing sufficient active sites required for the process of glucose electrocatlysis. Moreover, the unique core-shell structure promotes the catalytic activity towards glucose oxidation due to the synergistic effect caused by the bimetallic oxide shell and the metallic core that is conductive to electron transport. Accordingly, the Cu-Ni/NF electrode exhibits a high sensitivity of 11.34 mA mM−1 cm-2, a low detection limit of 2 μM (S/N = 3), and a wide linear range of 1–600 μM for glucose detection. In addition, the electrode demonstrates such advantages as high selectivity, fast response time, and long duration stability. The designed Cu-Ni/NF electrode shows its massive potential of application for non-enzymatic glucose detection.

Original languageEnglish
Article number129687
JournalSensors and Actuators, B: Chemical
Publication statusPublished - 15-06-2021

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry


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