TY - JOUR
T1 - Deoxycholate amphotericin for histoplasmosis in a patient with poor kidney function
AU - Krishnan, Gokul
AU - Gupta, Nitin
AU - Saravu, Kavitha
AU - Hande, Handattu Manjunath
AU - Khanna, Ruchee
N1 - Publisher Copyright:
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
PY - 2021/8/26
Y1 - 2021/8/26
N2 - A 48-year-old male patient living with HIV presented to our hospital with fever and weight loss. On evaluation, he was found to have pancytopenia, deranged liver and kidney function. CD4 count was 13 cells/uL. Bone marrow examination done because of pancytopenia showed yeast forms of histoplasmosis. Although liposomal amphotericin B is preferred for induction, he was treated with deoxycholate amphotericin B despite poor kidney function because of financial constraints. He was treated for 12 days with intravenous amphotericin, during which his clinical condition significantly improved. He was discharged on oral itraconazole.
AB - A 48-year-old male patient living with HIV presented to our hospital with fever and weight loss. On evaluation, he was found to have pancytopenia, deranged liver and kidney function. CD4 count was 13 cells/uL. Bone marrow examination done because of pancytopenia showed yeast forms of histoplasmosis. Although liposomal amphotericin B is preferred for induction, he was treated with deoxycholate amphotericin B despite poor kidney function because of financial constraints. He was treated for 12 days with intravenous amphotericin, during which his clinical condition significantly improved. He was discharged on oral itraconazole.
UR - http://www.scopus.com/inward/record.url?scp=85115142568&partnerID=8YFLogxK
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U2 - 10.1136/bcr-2021-243984
DO - 10.1136/bcr-2021-243984
M3 - Article
C2 - 34446514
AN - SCOPUS:85115142568
SN - 1757-790X
VL - 14
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 8
ER -
