TY - JOUR
T1 - Determination of racecadotril by spectrophotometric method in bulk drug and its formulation
AU - Shirwaikar, A.
AU - Prabu, S.L.
AU - Kumar, C.D.
AU - Rajendran, K.
AU - Joseph, A.
N1 - Cited By :1
Export Date: 10 November 2017
CODEN: INDRB
Correspondence Address: Shirwaikar, A.; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal - 576 104, India; email: [email protected]
References: Metheson, A.J., Noble, S., Racecadotril (2000) Drugs, 59, pp. 829-835; Bhan, M.K., Bhatnagar, S., Racecadotril in acute diarrhea-reply (2005) Indian Pediatr., 42, pp. 502-503; Schwartz, J.-C., Racecadotril: A new approach to the treatment of diarrhoea (2000) International Journal of Antimicrobial Agents, 14 (1), pp. 75-79. , DOI 10.1016/S0924-8579(99)00151-X, PII S092485799900151X; ICH Harmonized Tripartite Guideline, Recommended for Adoption for Step 4 of the ICH Process on 6 November 1996 by the ICH Steering Committee
PY - 2007
Y1 - 2007
N2 - A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 × 10 3 in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.
AB - A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 × 10 3 in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.
M3 - Article
SN - 0019-462X
VL - 44
SP - 13
EP - 15
JO - Indian Drugs
JF - Indian Drugs
IS - 1
ER -