Abstract
The aim of the present study was to develop controlled release formulation of Oxybutynin to maintain constant therapeutic levels of the drug for over 12 hrs. Karaya gum, Acacia and Tragacanth were employed as polymers. All the formulations were passed various physicochemical evaluation parameters and they were found to be within limits. From the dissolution studies it was evident that the formulation (F4) showed better and desired drug release pattern i.e., 98.14 % in 12 hours. It contains the Acacia polymer. It followed Zero order release kinetics mechanism.
| Original language | English |
|---|---|
| Pages (from-to) | 3854-3860 |
| Number of pages | 7 |
| Journal | Research Journal of Pharmacy and Technology |
| Volume | 13 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2020 |
All Science Journal Classification (ASJC) codes
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
- Pharmacology (medical)
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