Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Autofluorescence spectroscopy offer noninvasive and promising tools for the detection of alternations biochemical compositions of tissues and cells, in presence of disease. They have the added advantage of being highly objective due to the fact that diagnostic evaluation is by statistical methods, eliminating errors from lack of experience, fatigue factor, and subjectivity of visual perceptions. The present research work involves in designing and assembling of a low cost, miniature oral cancer screening device with for routine clinical applications. A miniature system was designed and assembled with much smaller and cost-effective components like compact light source and miniature spectrometer, in a hand-held unit configuration. The performance of the system was evaluated using animal -mouse- SCC model. The current system can be used in handheld operation, which makes it very useful for many applications like, screening of squamous cell carcinoma susceptible population.

Original languageEnglish
Title of host publicationClinical and Preclinical Optical Diagnostics
ISBN (Electronic)9781510612808
Publication statusPublished - 01-01-2017
EventClinical and Preclinical Optical Diagnostics 2017 - Munich, Germany
Duration: 25-06-201727-06-2017


ConferenceClinical and Preclinical Optical Diagnostics 2017

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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