Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma

Ajeetkumar Patil; Rao K. Swati; V. K. Unnikrishnan; Keerthilatha M. Pai; V. B. Kartha; Santhosh Chidangil

doi:10.1117/12.2282888

Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma

Ajeetkumar Patil
, Rao K. Swati
, V. K. Unnikrishnan
, Keerthilatha M. Pai
, V. B. Kartha
, Santhosh Chidangil

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Autofluorescence spectroscopy offer noninvasive and promising tools for the detection of alternations biochemical compositions of tissues and cells, in presence of disease. They have the added advantage of being highly objective due to the fact that diagnostic evaluation is by statistical methods, eliminating errors from lack of experience, fatigue factor, and subjectivity of visual perceptions. The present research work involves in designing and assembling of a low cost, miniature oral cancer screening device with for routine clinical applications. A miniature system was designed and assembled with much smaller and cost-effective components like compact light source and miniature spectrometer, in a hand-held unit configuration. The performance of the system was evaluated using animal -mouse- SCC model. The current system can be used in handheld operation, which makes it very useful for many applications like, screening of squamous cell carcinoma susceptible population.

Original language	English
Title of host publication	Clinical and Preclinical Optical Diagnostics
Editors	J. Quincy Brown, Ton G. van Leeuwen
Publisher	SPIE
Volume	10411
ISBN (Electronic)	9781510612808
DOIs	https://doi.org/10.1117/12.2282888
Publication status	Published - 01-01-2017
Event	Clinical and Preclinical Optical Diagnostics 2017 - Munich, Germany Duration: 25-06-2017 → 27-06-2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10411
ISSN (Print)	1605-7422

Conference

Conference	Clinical and Preclinical Optical Diagnostics 2017
Country/Territory	Germany
City	Munich
Period	25-06-17 → 27-06-17

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2282888

Cite this

Patil, A., Swati, R. K., Unnikrishnan, V. K., Pai, K. M., Kartha, V. B., & Chidangil, S. (2017). Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma. In J. Q. Brown, & T. G. van Leeuwen (Eds.), Clinical and Preclinical Optical Diagnostics (Vol. 10411). Article 104110V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10411). SPIE. https://doi.org/10.1117/12.2282888

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abstract = "Autofluorescence spectroscopy offer noninvasive and promising tools for the detection of alternations biochemical compositions of tissues and cells, in presence of disease. They have the added advantage of being highly objective due to the fact that diagnostic evaluation is by statistical methods, eliminating errors from lack of experience, fatigue factor, and subjectivity of visual perceptions. The present research work involves in designing and assembling of a low cost, miniature oral cancer screening device with for routine clinical applications. A miniature system was designed and assembled with much smaller and cost-effective components like compact light source and miniature spectrometer, in a hand-held unit configuration. The performance of the system was evaluated using animal -mouse- SCC model. The current system can be used in handheld operation, which makes it very useful for many applications like, screening of squamous cell carcinoma susceptible population.",

author = "Ajeetkumar Patil and Swati, \{Rao K.\} and Unnikrishnan, \{V. K.\} and Pai, \{Keerthilatha M.\} and Kartha, \{V. B.\} and Santhosh Chidangil",

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Patil, A, Swati, RK, Unnikrishnan, VK, Pai, KM, Kartha, VB & Chidangil, S 2017, Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma. in JQ Brown & TG van Leeuwen (eds), Clinical and Preclinical Optical Diagnostics. vol. 10411, 104110V, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10411, SPIE, Clinical and Preclinical Optical Diagnostics 2017, Munich, Germany, 25-06-17. https://doi.org/10.1117/12.2282888

Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma. / Patil, Ajeetkumar; Swati, Rao K.; Unnikrishnan, V. K. et al.
Clinical and Preclinical Optical Diagnostics. ed. / J. Quincy Brown; Ton G. van Leeuwen. Vol. 10411 SPIE, 2017. 104110V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10411).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

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AU - Patil, Ajeetkumar

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AU - Unnikrishnan, V. K.

AU - Pai, Keerthilatha M.

AU - Kartha, V. B.

AU - Chidangil, Santhosh

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AB - Autofluorescence spectroscopy offer noninvasive and promising tools for the detection of alternations biochemical compositions of tissues and cells, in presence of disease. They have the added advantage of being highly objective due to the fact that diagnostic evaluation is by statistical methods, eliminating errors from lack of experience, fatigue factor, and subjectivity of visual perceptions. The present research work involves in designing and assembling of a low cost, miniature oral cancer screening device with for routine clinical applications. A miniature system was designed and assembled with much smaller and cost-effective components like compact light source and miniature spectrometer, in a hand-held unit configuration. The performance of the system was evaluated using animal -mouse- SCC model. The current system can be used in handheld operation, which makes it very useful for many applications like, screening of squamous cell carcinoma susceptible population.

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Patil A, Swati RK, Unnikrishnan VK, Pai KM, Kartha VB, Chidangil S. Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma. In Brown JQ, van Leeuwen TG, editors, Clinical and Preclinical Optical Diagnostics. Vol. 10411. SPIE. 2017. 104110V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2282888

Development of a miniature autofluorescence device for the early diagnosis of squamous cell carcinoma

Abstract

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UN SDGs

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