Disseminated Nocardia asiatica infection in an immunocompromised individual: A rare entity needs careful vigilance

Barnini Banerjee; Rohit Gupta; Muralidhar Varma; Chiranjay Mukhopadhyay; Tushar Shaw

doi:10.1016/j.jiph.2018.12.008

Disseminated Nocardia asiatica infection in an immunocompromised individual: A rare entity needs careful vigilance

Barnini Banerjee, Rohit Gupta, Muralidhar Varma, Chiranjay Mukhopadhyay^*, Tushar Shaw

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Nocardia asteroides complex and Nocardia brasiliensis are common etiological agents of disseminated nocardiosis among immunocompromised individuals. Here we reported an uncommon case of disseminated nocardiosis with the involvement of lung, brain, soft tissue & pancreas by a rarely isolated species Nocardia asiatica in a HIV infected individual. Diagnosis was initially misinterpreted as tuberculosis based on the clinical and radiological findings. The isolate was identified to the species level with a 16S rRNA gene analysis & in vitro susceptibility was done as resistance is not uncommon among them. Clinical cure & radiological regression of lesions was observed except for brain after treatment with meropenem, amikacin & cotrimoxazole.

Original language	English
Pages (from-to)	167-170
Number of pages	4
Journal	Journal of Infection and Public Health
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/j.jiph.2018.12.008
Publication status	Published - 01-03-2019

All Science Journal Classification (ASJC) codes

Public Health, Environmental and Occupational Health
Infectious Diseases

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jiph.2018.12.008

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title = "Disseminated Nocardia asiatica infection in an immunocompromised individual: A rare entity needs careful vigilance",

abstract = "Nocardia asteroides complex and Nocardia brasiliensis are common etiological agents of disseminated nocardiosis among immunocompromised individuals. Here we reported an uncommon case of disseminated nocardiosis with the involvement of lung, brain, soft tissue & pancreas by a rarely isolated species Nocardia asiatica in a HIV infected individual. Diagnosis was initially misinterpreted as tuberculosis based on the clinical and radiological findings. The isolate was identified to the species level with a 16S rRNA gene analysis & in vitro susceptibility was done as resistance is not uncommon among them. Clinical cure & radiological regression of lesions was observed except for brain after treatment with meropenem, amikacin & cotrimoxazole.",

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AU - Gupta, Rohit

AU - Varma, Muralidhar

AU - Mukhopadhyay, Chiranjay

AU - Shaw, Tushar

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AB - Nocardia asteroides complex and Nocardia brasiliensis are common etiological agents of disseminated nocardiosis among immunocompromised individuals. Here we reported an uncommon case of disseminated nocardiosis with the involvement of lung, brain, soft tissue & pancreas by a rarely isolated species Nocardia asiatica in a HIV infected individual. Diagnosis was initially misinterpreted as tuberculosis based on the clinical and radiological findings. The isolate was identified to the species level with a 16S rRNA gene analysis & in vitro susceptibility was done as resistance is not uncommon among them. Clinical cure & radiological regression of lesions was observed except for brain after treatment with meropenem, amikacin & cotrimoxazole.

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Disseminated Nocardia asiatica infection in an immunocompromised individual: A rare entity needs careful vigilance

Abstract

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