TY - JOUR
T1 - Dissolution development of valdecoxib tablets
AU - Subramanian, G.
AU - Faisal, M.
AU - Karthik, A.
AU - Bhat, V.
AU - Ranjithkumar, A.
AU - Udupa, N.
N1 - Cited By :2
Export Date: 10 November 2017
CODEN: IJSID
Correspondence Address: Udupa, N.; Manipal College of Pharmaceutical Sciences, MAHE, Manipal-576 104, India; email: [email protected]
Chemicals/CAS: dodecyl sulfate sodium, 151-21-3; polysorbate 80, 8050-83-7, 9005-65-6; valdecoxib, 181695-72-7; water, 7732-18-5
Tradenames: revaldo 20, Bangalore, India; valus, Glenmark, India
Manufacturers: Bangalore, India; Glenmark, India; IPCA, India; Qualigens, India
References: Kurumbali, R.G., Stevens, A.M., Gierse, J.K., McDonald, J.J., Stegman, R.A., Pak, J.Y., Gildehaus, D., Stalling, W.C., (1996) Nature, 384, p. 644; Peterson, W.L., Cryer, B., (1999) J. Amer. Med. Assn, 282, p. 1961; Gander, B., Ventourase, K., Gurny, R., Doelkar, E., (1985) Int. J. Pharm, 27, p. 117; Gibladi, M., Feldman, S., (1967) J. Pharm. Sci, 56, p. 1238; Shah, V.P., Konecny, J.J., Everett, R.L., McCullough, B., Skelly, J.P., (1989) Pharm. Res, 6, p. 612; United States of Pharmacopoeia 23, US Pharmacopoeia Convention, 1995, 267; Abdou, H.M., Hanna, S., Mohammad, N., (2000) Remington: The Science and Practice of Pharmacy, 1, p. 655. , Gennaro, A.R, Eds, 20th Edn, Lippncott Williams and Wilkins, Baltimore, Maryland; Schott, H., Kwan, L.C., Feldman, S., (1982) J. Pharm. Sci, 71, p. 1038; Babu, M.M.G.V., Shankar, G.V., Shankar, H.K., Seshayana, A., Kumar, K.N., Murthy, R.K.V., (2002) Indian J. Pharm. Sci, p. 588
PY - 2006/2/1
Y1 - 2006/2/1
N2 - Valdecoxib is a nonsteroidal antiinflammatory drug, and it is listed in class 2 of biopharmaceutic classification of drugs. Valdecoxib is a poorly water-soluble and highly permeable drug. In the present study a new dissolution medium was developed, as there is no official dissolution medium available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37°. Solubility data revealed that addition of surfactant may be suitable as dissolution medium. The concentration of 0.6% w/v sodium lauryl sulphate in water could be a suitable dissolution medium. The discriminating power of the selected dissolution medium (0.6% sodium lauryl sulphate in water) relative to the other dissolution mediums was evaluated. The selected dissolution medium was used for the evaluation of valdecoxib tablets.
AB - Valdecoxib is a nonsteroidal antiinflammatory drug, and it is listed in class 2 of biopharmaceutic classification of drugs. Valdecoxib is a poorly water-soluble and highly permeable drug. In the present study a new dissolution medium was developed, as there is no official dissolution medium available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37°. Solubility data revealed that addition of surfactant may be suitable as dissolution medium. The concentration of 0.6% w/v sodium lauryl sulphate in water could be a suitable dissolution medium. The discriminating power of the selected dissolution medium (0.6% sodium lauryl sulphate in water) relative to the other dissolution mediums was evaluated. The selected dissolution medium was used for the evaluation of valdecoxib tablets.
UR - https://www.scopus.com/pages/publications/33846130636
UR - https://www.scopus.com/pages/publications/33846130636#tab=citedBy
M3 - Article
AN - SCOPUS:33846130636
SN - 0250-474X
VL - 68
SP - 680
EP - 682
JO - Indian Journal of Pharmaceutical Sciences
JF - Indian Journal of Pharmaceutical Sciences
IS - 5
ER -