xosomes generated from human bone marrow derived mesenchymal stem cells (hMSCs) display antiinflammatory and neuroprotective activity of hMSCs. Our recent study in a model of status epilepticus (SE) has shown that intranasally (IN) administered hMSC-derived A1-exosomes reach different parts of the brain including the hippocampus within 6 hours (Long et al., PNAS, 2017).
|Title of host publication||Distribution of mesenchymal stem cell-derived exosomes in the intact and injured brain following intranasal administration|
|Publisher||Society for Neuroscience|
|Publication status||Published - 15-11-2017|