Drug induced nephrotoxicity and associated factors a narrative review

N. Nagalakshmi, V. Manju, Basavaraj Poojar, Ravi K. Sori, Amrita Parida

Research output: Contribution to journalArticlepeer-review


Drugs are a common reason for kidney injury. Antibiotic like gentamicin which is clinically a highly effective drug, is not preferred by physicians primarily because of the renal damage caused by it. Medication-induced renal injury has an intricate mechanism that includes a multitude of elements together with the innate nature of medications, innate patient characteristics that increase the chances of renal damage, and the pharmacokinetics of the drug. A particular drug can produce varied amount of damage in different individuals, which implies that the risk is not same for all. The reason behind this is that, there are different factors which determine the amount of renal damage that occurs due to drugs. In this article, we have reviewed the various elements linked to drug-induced nephrotoxicity.

Original languageEnglish
Pages (from-to)5563-5570
Number of pages8
JournalJournal of Medical Pharmaceutical and Allied Sciences
Issue number1
Publication statusPublished - 01-2023

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)


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