TY - JOUR
T1 - Effect of curcumin analogues on oxidation of haemoglobin and lysis of erythrocytes
AU - Venkatesan, P.
AU - Unnikrishnan, M.K.
AU - Sudheer Kumar, M.
AU - Rao, M.N.A.
N1 - Cited By :11
Export Date: 10 November 2017
CODEN: CUSCA
Correspondence Address: Venkatesan, P.; Divi's Laboratories Ltd., C-26, Industrial Estate, Sanath Nagar, Hyderabad 500 018, India; email: [email protected]
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PY - 2003
Y1 - 2003
N2 - A number of ring-substituted analogues of curcumin were studied for their ability to prevent nitrite-induced oxidation of haemoglobin and lysis of erythrocytes. Phenolic analogues were more active than their non-phenolic counterparts. Many of the active compounds were more potent than standard antioxidants such as tocopherol and trolox. Tetrahydrocurcumin showed higher activity than curcumin, suggesting that unsaturation in the central portion of curcumin may not be important for activity.
AB - A number of ring-substituted analogues of curcumin were studied for their ability to prevent nitrite-induced oxidation of haemoglobin and lysis of erythrocytes. Phenolic analogues were more active than their non-phenolic counterparts. Many of the active compounds were more potent than standard antioxidants such as tocopherol and trolox. Tetrahydrocurcumin showed higher activity than curcumin, suggesting that unsaturation in the central portion of curcumin may not be important for activity.
M3 - Article
SN - 0011-3891
VL - 84
SP - 74
EP - 78
JO - Current Science
JF - Current Science
IS - 1
ER -