TY - JOUR
T1 - Effect of Family-Centered Care Interventions on Motor and Neurobehavior Development of Very Preterm Infants
T2 - A Systematic Review and Meta-Analysis
AU - Raghupathy, Manasa Kolibylu
AU - Parsekar, Shradha S.
AU - Nayak, Shubha R.
AU - Karun, Kalesh M.
AU - Khurana, Sonia
AU - Spittle, Alicia J.
AU - Lewis, Leslie Edward S.
AU - Rao, Bhamini Krishna
N1 - Publisher Copyright:
© 2025 The Author(s). Published with license by Taylor & Francis Group, LLC.
PY - 2025
Y1 - 2025
N2 - Aim: To assess the effectiveness of family-centered care (FCC) interventions on motor and neurobehavior development of very preterm infants. Method: Randomized and quasi-randomized trials assessing the effect of FCC on motor and neurobehavioral outcomes in very preterm infants (28–32 wk gestation) were included. Five electronic databases and grey literature were searched from January 2010 to August 2022. Two reviewers independently screened the titles/abstracts and full texts, assessed the risk of bias, and extracted data. The Cochrane Risk of Bias 2.0 Tool and GRADE were used for risk and evidence certainty assessments. Meta-analysis or narrative synthesis was performed based on data availability and heterogeneity. Results: Seventeen trials with 21 publications were included. GRADE showed low to moderate evidence. At 24 months, FCC interventions improved motor development (Mean Difference (MD):5.00, 95% CI: 2.58–7.42), cognitive development (MD: 3.64, 95% CI: 1.15–6.12), and behavior development (MD: −2.40, 95% CI: −4.32, −0.48) compared to control groups. Further, the FCC showed minimal or inconclusive effects on language, communication, and personal social development measured anytime between newborn and 24 months of age. Conclusions: Early initiated FCC interventions can be a promising approach to improve motor, cognition, and behavioral development in very preterm infants.
AB - Aim: To assess the effectiveness of family-centered care (FCC) interventions on motor and neurobehavior development of very preterm infants. Method: Randomized and quasi-randomized trials assessing the effect of FCC on motor and neurobehavioral outcomes in very preterm infants (28–32 wk gestation) were included. Five electronic databases and grey literature were searched from January 2010 to August 2022. Two reviewers independently screened the titles/abstracts and full texts, assessed the risk of bias, and extracted data. The Cochrane Risk of Bias 2.0 Tool and GRADE were used for risk and evidence certainty assessments. Meta-analysis or narrative synthesis was performed based on data availability and heterogeneity. Results: Seventeen trials with 21 publications were included. GRADE showed low to moderate evidence. At 24 months, FCC interventions improved motor development (Mean Difference (MD):5.00, 95% CI: 2.58–7.42), cognitive development (MD: 3.64, 95% CI: 1.15–6.12), and behavior development (MD: −2.40, 95% CI: −4.32, −0.48) compared to control groups. Further, the FCC showed minimal or inconclusive effects on language, communication, and personal social development measured anytime between newborn and 24 months of age. Conclusions: Early initiated FCC interventions can be a promising approach to improve motor, cognition, and behavioral development in very preterm infants.
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U2 - 10.1080/01942638.2024.2449387
DO - 10.1080/01942638.2024.2449387
M3 - Review article
AN - SCOPUS:85215066099
SN - 0194-2638
JO - Physical and Occupational Therapy in Pediatrics
JF - Physical and Occupational Therapy in Pediatrics
ER -