Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains

Mallika Maiya; S. J. Akshatha; K. L. Shobha; Vivekananda Shenoy; K. Subrahmanya Bhat

Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains

Mallika Maiya, S. J. Akshatha, K. L. Shobha, Vivekananda Shenoy^*, K. Subrahmanya Bhat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.

Original language	English
Pages (from-to)	466-470
Number of pages	5
Journal	Research Journal of Pharmaceutical, Biological and Chemical Sciences
Volume	6
Issue number	2
Publication status	Published - 01-01-2015

All Science Journal Classification (ASJC) codes

General Biochemistry,Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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title = "Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains",

abstract = "We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.",

author = "Mallika Maiya and Akshatha, {S. J.} and Shobha, {K. L.} and Vivekananda Shenoy and {Subrahmanya Bhat}, K.",

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TY - JOUR

T1 - Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains

AU - Maiya, Mallika

AU - Akshatha, S. J.

AU - Shobha, K. L.

AU - Shenoy, Vivekananda

AU - Subrahmanya Bhat, K.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.

AB - We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.

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M3 - Article

AN - SCOPUS:84925145448

SN - 0975-8585

VL - 6

SP - 466

EP - 470

JO - Research Journal of Pharmaceutical, Biological and Chemical Sciences

JF - Research Journal of Pharmaceutical, Biological and Chemical Sciences

IS - 2

ER -

Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains

Abstract

All Science Journal Classification (ASJC) codes

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