Abstract
To evaluate the effect of vanillin on the lipid profile of high fat diet induced hyperlipidemia in rats, the hyperlipidemia was induced by feeding cholesterol-rich high fat diet for 45 days in wistar rats of either sex. The reduction in the triglycerides and VLDL-C was significant at 200 & 400 mg/kg dose of vanillin compared to atorvastatin group. Reduction in total cholesterol was significant at 200 and 400 mg/kg doses compared to hyperlipidemic control. The results demonstrate that vanillin at a dose of 200 and 400 mg/kg body weight lowers the serum triglyceride, VLDL-C and total cholesterol level significantly in high fat diet induced hyperlipidemic rats. However there was no significant effect on the lipid profile at 100 mg/kg dose. There were no statistically significant changes in the HDL-C and LDL-C levels at any of the given doses.
| Original language | English |
|---|---|
| Pages (from-to) | 288-291 |
| Number of pages | 4 |
| Journal | Indian Journal of Experimental Biology |
| Volume | 51 |
| Issue number | 4 |
| Publication status | Published - 01-04-2013 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Molecular Biology
- Cell Biology