Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats

N. A. Vinodini; Pratik Kumar Chatterjee; Kunal; V. B. Suman; K. S. Rashmi; A. K. Nayanatara; N. Anupama; Ramesh M. Bhat; P. Sheela Joice

doi:10.5530/pj.2019.11.109

Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats

N. A. Vinodini
, Pratik Kumar Chatterjee^*
, Kunal
, V. B. Suman
, K. S. Rashmi
, A. K. Nayanatara
, N. Anupama
, Ramesh M. Bhat
, P. Sheela Joice

^*Corresponding author for this work

Department of Physiology, Kasturba Medical College, Mangalore

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

Original language	English
Pages (from-to)	689-693
Number of pages	5
Journal	Pharmacognosy Journal
Volume	11
Issue number	4
DOIs	https://doi.org/10.5530/pj.2019.11.109
Publication status	Published - 01-01-2019

All Science Journal Classification (ASJC) codes

Pharmacology
Drug Discovery

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title = "Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats",

abstract = "Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.",

author = "Vinodini, \{N. A.\} and Chatterjee, \{Pratik Kumar\} and Kunal and Suman, \{V. B.\} and Rashmi, \{K. S.\} and Nayanatara, \{A. K.\} and N. Anupama and Bhat, \{Ramesh M.\} and \{Sheela Joice\}, P.",

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year = "2019",

month = jan,

day = "1",

doi = "10.5530/pj.2019.11.109",

language = "English",

volume = "11",

pages = "689--693",

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T1 - Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count

T2 - An experiment on cadmium exposed rats

AU - Vinodini, N. A.

AU - Chatterjee, Pratik Kumar

AU - Kunal, null

AU - Suman, V. B.

AU - Rashmi, K. S.

AU - Nayanatara, A. K.

AU - Anupama, N.

AU - Bhat, Ramesh M.

AU - Sheela Joice, P.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

AB - Aims and Objective:To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated, group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

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DO - 10.5530/pj.2019.11.109

M3 - Article

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SN - 0975-3575

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JO - Pharmacognosy Journal

JF - Pharmacognosy Journal

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ER -

Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An experiment on cadmium exposed rats

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