Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns

I. Karuna Sagar; C. N. Nagesha; P. Gundu Rao

doi:10.1016/0305-4179(79)90011-1

Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns

I. Karuna Sagar, C. N. Nagesha, P. Gundu Rao

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.

Original language	English
Pages (from-to)	131-133
Number of pages	3
Journal	Burns
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/0305-4179(79)90011-1
Publication status	Published - 01-01-1979
Externally published	Yes

All Science Journal Classification (ASJC) codes

Surgery
Emergency Medicine
Critical Care and Intensive Care Medicine

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10.1016/0305-4179(79)90011-1

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title = "Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns",

abstract = "The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.",

author = "{Karuna Sagar}, I. and Nagesha, {C. N.} and {Gundu Rao}, P.",

year = "1979",

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AU - Karuna Sagar, I.

AU - Nagesha, C. N.

AU - Gundu Rao, P.

PY - 1979/1/1

Y1 - 1979/1/1

N2 - The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.

AB - The efficacy of topical therapy with silver sulphadiazine and zinc sulphadiazine was compared with that of zinc sulphate in controlling pseudomonas infection of burns in mice. Both zinc and silver sulphadiazine reduced the mortality by 18 per cent but zinc sulphate failed to reduce mortality at all. The results indicate that in vivo, the antibacterial activity of zinc ions may be supplemented by that of sulphadiazine moiety.

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JF - Burns

IS - 2

ER -

Effectiveness of zinc sulphadiazine, zinc sulphate and silver sulphadiazine in the topical therapy of pseudomonas infection in burns

Abstract

All Science Journal Classification (ASJC) codes

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