TY - JOUR
T1 - Effects of home-based exercise training on functional outcomes and quality of life in patients with pulmonary hypertension
T2 - A randomized clinical trial
AU - Babu, Abraham Samuel
AU - Padmakumar, Ramachandran
AU - Nayak, Krishnanand
AU - Shetty, Ranjan
AU - Mohapatra, Aswini Kumar
AU - Maiya, Arun G.
N1 - Funding Information:
A.S.B. received the Tom Lantos Innovation in Community Service Award for development of the Pulmonary Hypertension Manual (PulHMan). The Pulmonary Hypertension Association's Tom Lantos Innovation in Community Service Award is funded by Gilead . All other authors have no other conflicts of interest.
Funding Information:
The authors acknowledge the support received from Ms. Jyothi, Department of Cardiovascular Technology, SOAHS, Manipal Academy of Higher Education, Manipal , and Dr. RL Kamath, Department of Cardiology, Kasturba Medical College, Mangalore .
Funding Information:
A.S.B. received the Tom Lantos Innovation in Community Service Award for development of the Pulmonary Hypertension Manual (PulHMan). The Pulmonary Hypertension Association's Tom Lantos Innovation in Community Service Award is funded by Gilead. All other authors have no other conflicts of interest.The development of the Pulmonary Hypertension Manual (PulHMan) was supported by the Tom Lantos Innovation in Community Service Award (2012). The Pulmonary Hypertension Association's Tom Lantos Innovation in Community Service Award is funded by Gilead.The authors acknowledge the support received from Ms. Jyothi, Department of Cardiovascular Technology, SOAHS, Manipal Academy of Higher Education, Manipal, and Dr. RL Kamath, Department of Cardiology, Kasturba Medical College, Mangalore.
Publisher Copyright:
© 2019 Cardiological Society of India
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Objectives: The objective of this study was to assess the effects of home-based exercise training (HBET) on function and quality of life (QoL) in patients with pulmonary hypertension (PH). Methods: A prospective, nonblinded, randomized clinical trial was carried out on 84 medically stable patients with PH belonging to any functional class or etiology and of either sex. Patients were randomized to either standard care or HBET. Both groups also received education using the Pulmonary Hypertension Manual (PulHMan). Outcomes included functional capacity from 6-min walk distance (6MWD), QoL using the Medical Outcomes Survey Short Form – 36, functional class (FC), and right heart indices (right ventricular systolic pressure [RVSP] and tricuspid annular plane systolic excursion [TAPSE]) and were assessed at entry and after 12 weeks. Results: HBET improved 6MWD by 48.5 m and 13 m in the experimental and control groups, respectively (p < 0.001). QoL showed statistical improvements after HBET between the groups for the physical and mental components and for the various subdomains (except body pain). Furthermore, FC improved by one grade with HBET (p < 0.001). Conclusion: HBET program improved functional capacity, QoL, and FC in patients with PH.
AB - Objectives: The objective of this study was to assess the effects of home-based exercise training (HBET) on function and quality of life (QoL) in patients with pulmonary hypertension (PH). Methods: A prospective, nonblinded, randomized clinical trial was carried out on 84 medically stable patients with PH belonging to any functional class or etiology and of either sex. Patients were randomized to either standard care or HBET. Both groups also received education using the Pulmonary Hypertension Manual (PulHMan). Outcomes included functional capacity from 6-min walk distance (6MWD), QoL using the Medical Outcomes Survey Short Form – 36, functional class (FC), and right heart indices (right ventricular systolic pressure [RVSP] and tricuspid annular plane systolic excursion [TAPSE]) and were assessed at entry and after 12 weeks. Results: HBET improved 6MWD by 48.5 m and 13 m in the experimental and control groups, respectively (p < 0.001). QoL showed statistical improvements after HBET between the groups for the physical and mental components and for the various subdomains (except body pain). Furthermore, FC improved by one grade with HBET (p < 0.001). Conclusion: HBET program improved functional capacity, QoL, and FC in patients with PH.
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U2 - 10.1016/j.ihj.2019.03.002
DO - 10.1016/j.ihj.2019.03.002
M3 - Article
AN - SCOPUS:85063520574
SN - 0019-4832
VL - 71
SP - 161
EP - 165
JO - Indian Heart Journal
JF - Indian Heart Journal
IS - 2
ER -