TY - JOUR
T1 - Efficacy of He-Ne Laser in the prevention and treatment of radiotherapy-induced oral mucositis in oral cancer patients
AU - Arora, Honey
AU - Pai, Keerthilatha M.
AU - Maiya, Arun
AU - Vidyasagar, M. S.
AU - Rajeev, A.
PY - 2008/2/1
Y1 - 2008/2/1
N2 - Objective: The objective of this study was to evaluate the efficacy of low-level lasers for the prevention and treatment of radiotherapy-induced oral mucositis in oral cancer patients. Material and methods: Twenty-four hospitalized patients with oral cancer, scheduled to undergo radiotherapy at KMC, Manipal, were enrolled in the present study and assigned to laser (Group I)/control group (Group II). They were treated using He-Ne laser (λ = 632.8nm, output = 10 mW and energy density = 1.8 J/cm2). Patients were subjected to treatment using laser scanner for 8 days and subsequently were treated using laser probe at 6 anatomic sites in the oral cavity for 5 minutes each. The patients were evaluated on each day of treatment for pain severity (NRS), functional impairment (FIS), and oral mucositis (RTOG) and were followed until the end of cancer treatment. Statistical analysis was done using SPSS version 10. Results: Laser therapy applied prophylactically during radiotherapy can reduce the severity of oral mucositis, severity of pain, and functional impairment.
AB - Objective: The objective of this study was to evaluate the efficacy of low-level lasers for the prevention and treatment of radiotherapy-induced oral mucositis in oral cancer patients. Material and methods: Twenty-four hospitalized patients with oral cancer, scheduled to undergo radiotherapy at KMC, Manipal, were enrolled in the present study and assigned to laser (Group I)/control group (Group II). They were treated using He-Ne laser (λ = 632.8nm, output = 10 mW and energy density = 1.8 J/cm2). Patients were subjected to treatment using laser scanner for 8 days and subsequently were treated using laser probe at 6 anatomic sites in the oral cavity for 5 minutes each. The patients were evaluated on each day of treatment for pain severity (NRS), functional impairment (FIS), and oral mucositis (RTOG) and were followed until the end of cancer treatment. Statistical analysis was done using SPSS version 10. Results: Laser therapy applied prophylactically during radiotherapy can reduce the severity of oral mucositis, severity of pain, and functional impairment.
UR - http://www.scopus.com/inward/record.url?scp=38949185006&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38949185006&partnerID=8YFLogxK
U2 - 10.1016/j.tripleo.2007.07.043
DO - 10.1016/j.tripleo.2007.07.043
M3 - Article
C2 - 18230388
AN - SCOPUS:38949185006
SN - 1079-2104
VL - 105
SP - 180-186.e1
JO - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
JF - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
IS - 2
ER -
