Electrospun nanofibres and their biomedical applications

Recent research in biomedical science specifically in the area of electrospinning nanofibers have been documented to have a great value addition in terms of its various applications. The basic principle of fabricating the nanofibers involves the use of electric force to draw charged threads to convert it into nanoparticles. BCS class II drug molecules having the solubility issues, affects the bioavailability of the formulation, is a big challenge in recent years. The use of electrospinning nanofiber technology can be used as an effective platform to enhance their bioavailability and to achieve a controlled release of drug in an effective manner. The various biomedical applications of these nanofibers involve specifically in the area of drug delivery, tissue engineering and enzyme immobilization. This article aims to summarize the importance of electrospun nanofibers with its fabrication techniques, processing parameters and various applications in the field of biomedical sciences.