Eltrombopag-induced Cortical Vein Thrombosis: A Case Report

Tarun Selvarajan; Vasudeva Acharya; Cynthia Amrutha Sukumar; B. Nandakrishna; Nagraj Kamath; Rukmoni Balasubramanian

Eltrombopag-induced Cortical Vein Thrombosis: A Case Report

Tarun Selvarajan
, Vasudeva Acharya
, Cynthia Amrutha Sukumar
, B. Nandakrishna^*
, Nagraj Kamath
, Rukmoni Balasubramanian

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Eltrombopag, a thrombopoietin receptor agonist is widely used in the treatment of immune thrombocytopenic purpura (ITP), aplastic anaemia and post-transplant cytopenia. Eltrombopag is used as second-line treatment in ITP. We describe a rare and life-threatening complication of this drug namely cortical venous thrombosis in a patient with ITP. Pathogenetic mechanisms behind the thrombosis may vary from case to case. Thrombosis may be linked to the platelet count or additional thrombophilic states. Regular monitoring of patients on therapy with Eltrombopag is required to avoid these complications.

Original language	English
Pages (from-to)	221-223
Number of pages	3
Journal	Journal, Indian Academy of Clinical Medicine
Volume	24
Issue number	3-4
Publication status	Published - 01-07-2023

All Science Journal Classification (ASJC) codes

General Medicine

Cite this

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title = "Eltrombopag-induced Cortical Vein Thrombosis: A Case Report",

abstract = "Eltrombopag, a thrombopoietin receptor agonist is widely used in the treatment of immune thrombocytopenic purpura (ITP), aplastic anaemia and post-transplant cytopenia. Eltrombopag is used as second-line treatment in ITP. We describe a rare and life-threatening complication of this drug namely cortical venous thrombosis in a patient with ITP. Pathogenetic mechanisms behind the thrombosis may vary from case to case. Thrombosis may be linked to the platelet count or additional thrombophilic states. Regular monitoring of patients on therapy with Eltrombopag is required to avoid these complications.",

author = "Tarun Selvarajan and Vasudeva Acharya and Sukumar, \{Cynthia Amrutha\} and B. Nandakrishna and Nagraj Kamath and Rukmoni Balasubramanian",

year = "2023",

month = jul,

day = "1",

language = "English",

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journal = "Journal, Indian Academy of Clinical Medicine",

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TY - JOUR

T1 - Eltrombopag-induced Cortical Vein Thrombosis

T2 - A Case Report

AU - Selvarajan, Tarun

AU - Acharya, Vasudeva

AU - Sukumar, Cynthia Amrutha

AU - Nandakrishna, B.

AU - Kamath, Nagraj

AU - Balasubramanian, Rukmoni

PY - 2023/7/1

Y1 - 2023/7/1

N2 - Eltrombopag, a thrombopoietin receptor agonist is widely used in the treatment of immune thrombocytopenic purpura (ITP), aplastic anaemia and post-transplant cytopenia. Eltrombopag is used as second-line treatment in ITP. We describe a rare and life-threatening complication of this drug namely cortical venous thrombosis in a patient with ITP. Pathogenetic mechanisms behind the thrombosis may vary from case to case. Thrombosis may be linked to the platelet count or additional thrombophilic states. Regular monitoring of patients on therapy with Eltrombopag is required to avoid these complications.

AB - Eltrombopag, a thrombopoietin receptor agonist is widely used in the treatment of immune thrombocytopenic purpura (ITP), aplastic anaemia and post-transplant cytopenia. Eltrombopag is used as second-line treatment in ITP. We describe a rare and life-threatening complication of this drug namely cortical venous thrombosis in a patient with ITP. Pathogenetic mechanisms behind the thrombosis may vary from case to case. Thrombosis may be linked to the platelet count or additional thrombophilic states. Regular monitoring of patients on therapy with Eltrombopag is required to avoid these complications.

UR - https://www.scopus.com/pages/publications/85185528584

UR - https://www.scopus.com/pages/publications/85185528584#tab=citedBy

M3 - Article

AN - SCOPUS:85185528584

SN - 0972-3560

VL - 24

SP - 221

EP - 223

JO - Journal, Indian Academy of Clinical Medicine

JF - Journal, Indian Academy of Clinical Medicine

IS - 3-4

ER -

Eltrombopag-induced Cortical Vein Thrombosis: A Case Report

Abstract

All Science Journal Classification (ASJC) codes

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