Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study

N. Ananth; B. Balaji Ganesh; D. M. Vasudevan; Vivian D. Souza; Ashalatha V. Rao; Dinesh Nambiar

doi:10.1007/BF02867875

Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study

N. Ananth, B. Balaji Ganesh, D. M. Vasudevan, Vivian D. Souza, Ashalatha V. Rao, Dinesh Nambiar

Research output: Contribution to journal › Article › peer-review

Abstract

In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.

Original language	English
Pages (from-to)	126-128
Number of pages	3
Journal	Indian Journal of Clinical Biochemistry
Volume	13
Issue number	2
DOIs	https://doi.org/10.1007/BF02867875
Publication status	Published - 01-01-1998
Externally published	Yes

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

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10.1007/BF02867875

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abstract = "In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.",

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AU - Ananth, N.

AU - Balaji Ganesh, B.

AU - Vasudevan, D. M.

AU - Souza, Vivian D.

AU - Rao, Ashalatha V.

AU - Nambiar, Dinesh

PY - 1998/1/1

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AB - In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.

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Enhancement of myeloperoxidase activity in wbcs in oral cancer patients treated with granulocyte macrophage colony stimulating factor (GM-CSF) - A pilot study

Abstract

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