Ensemble pharmacophore meets ensemble docking: A novel screening strategy for the identification of RIPK1 inhibitors

INIS

• proteins 100%
• kinases 100%
• receptors 100%
• screening 100%
• serine 100%
• threonine 100%
• apoptosis 50%
• protein structure 50%
• evaluation 16%
• diseases 16%
• range 16%
• extraction 16%
• inhibition 16%
• information 16%
• zinc 16%
• simulation 16%
• molecular dynamics method 16%

Biochemistry, Genetics and Molecular Biology

• Screening 100%
• Pharmacophore 100%
• Protein Serine-Threonine Kinase 100%
• Protein Structure 42%
• Protein 28%
• Cell Death 28%
• Necroptosis 28%
• Molecular Dynamics 28%
• Data Base 14%
• Electric Potential 14%
• Extraction 14%
• Apoptosis 14%
• Binding Site 14%

Chemistry

• Statistical Ensemble 100%