Escitalopram induced SIADH in an elderly female: A case study

Sudha Vidyasagar; Karthik Rao; Muralidhar Verma; Aswini Dutt Tripuraneni; Navin Patil; Dipanjan Bhattacharjee

Escitalopram induced SIADH in an elderly female: A case study

Sudha Vidyasagar
, Karthik Rao^*
, Muralidhar Verma
, Aswini Dutt Tripuraneni
, Navin Patil
, Dipanjan Bhattacharjee

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders. Here, we report a case where a 58 year old diabetic lady, when initiated on escitalopram for dysthymia developed severe hyponatraemia within 2 weeks. Further, we discuss other relevant cases that have been reported in the past with an eye on the management of SIADH and hyponatraemia.

Original language	English
Pages (from-to)	64-67
Number of pages	4
Journal	Psychopharmacology Bulletin
Volume	47
Issue number	4
Publication status	Published - 01-01-2017

All Science Journal Classification (ASJC) codes

Psychiatry and Mental health
Pharmacology (medical)

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Cite this

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title = "Escitalopram induced SIADH in an elderly female: A case study",

abstract = "Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders. Here, we report a case where a 58 year old diabetic lady, when initiated on escitalopram for dysthymia developed severe hyponatraemia within 2 weeks. Further, we discuss other relevant cases that have been reported in the past with an eye on the management of SIADH and hyponatraemia.",

author = "Sudha Vidyasagar and Karthik Rao and Muralidhar Verma and Tripuraneni, \{Aswini Dutt\} and Navin Patil and Dipanjan Bhattacharjee",

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TY - JOUR

T1 - Escitalopram induced SIADH in an elderly female

T2 - A case study

AU - Vidyasagar, Sudha

AU - Rao, Karthik

AU - Verma, Muralidhar

AU - Tripuraneni, Aswini Dutt

AU - Patil, Navin

AU - Bhattacharjee, Dipanjan

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders. Here, we report a case where a 58 year old diabetic lady, when initiated on escitalopram for dysthymia developed severe hyponatraemia within 2 weeks. Further, we discuss other relevant cases that have been reported in the past with an eye on the management of SIADH and hyponatraemia.

AB - Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders. Here, we report a case where a 58 year old diabetic lady, when initiated on escitalopram for dysthymia developed severe hyponatraemia within 2 weeks. Further, we discuss other relevant cases that have been reported in the past with an eye on the management of SIADH and hyponatraemia.

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M3 - Article

AN - SCOPUS:85041546514

SN - 0048-5764

VL - 47

SP - 64

EP - 67

JO - Psychopharmacology Bulletin

JF - Psychopharmacology Bulletin

IS - 4

ER -

Escitalopram induced SIADH in an elderly female: A case study

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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