Ethnic aspects of acute primary angle closure in a UK multicultural conurbation

Aim: To investigate the incidence and ethnic distribution of patients with symptomatic acute primary angle closure (APAC) who presented to a UK hospital serving a multicultural conurbation by a population-wide case series investigation. Methods: Case series chart review of patients aged 30 years and above, who required laser peripheral iridotomy (LPI) for a primary acute angle closure event over a 7-year period. Demographic data for cases were compared to the local resident census data. Results: A total of 46 local residents aged ≥30 years required LPI for APAC. In all, 96% of patients were Caucasian compared to the local resident population of 89% Caucasian. The overall annual APAC rate for Bolton was 4.14 cases per 100000 population (95% CI 3.03 -5.52). The standardised incidence ratio for the South Asian population was 0.78 (95% CI 0.02 -4.34) and 26.6 (95% CI 0.67 -148.40) for the Chinese population. Conclusions: APAC incidence in South Asians was similar to that among Caucasians. The incidence of APAC patients treated in this UK department is consistent with international experience. Individuals of Chinese ethnicity were at an enhanced risk of APAC. However, these results should be interpreted with caution, as patient numbers are small.