Evaluation of FEW ciprofloxacin (CIP) AND norfloxacin (NOR) formulations

N. Udupa; Leelavathi Bhat

doi:10.3109/03639049209038757

Evaluation of FEW ciprofloxacin (CIP) AND norfloxacin (NOR) formulations

N. Udupa^*, Leelavathi Bhat

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Formulations containing ciprofloxacin hydrochloride and norfloxacin for the treatment of ophthalmic and skin infections were made. The stability, bioavailability and therapeutic efficacy of the preparations were evaluated. These antibiotics were not systematically absorbed, when applied locally. Preparations were found more effective for the treatment of skin and eye infections. Betacyclodextrin improved the bioavailability of antibiotics.

Original language	English
Pages (from-to)	2197-2205
Number of pages	9
Journal	Drug Development and Industrial Pharmacy
Volume	18
Issue number	20
DOIs	https://doi.org/10.3109/03639049209038757
Publication status	Published - 1992

All Science Journal Classification (ASJC) codes

Drug Discovery
Pharmacology
Organic Chemistry
Molecular Medicine

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10.3109/03639049209038757

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abstract = "Formulations containing ciprofloxacin hydrochloride and norfloxacin for the treatment of ophthalmic and skin infections were made. The stability, bioavailability and therapeutic efficacy of the preparations were evaluated. These antibiotics were not systematically absorbed, when applied locally. Preparations were found more effective for the treatment of skin and eye infections. Betacyclodextrin improved the bioavailability of antibiotics.",

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AB - Formulations containing ciprofloxacin hydrochloride and norfloxacin for the treatment of ophthalmic and skin infections were made. The stability, bioavailability and therapeutic efficacy of the preparations were evaluated. These antibiotics were not systematically absorbed, when applied locally. Preparations were found more effective for the treatment of skin and eye infections. Betacyclodextrin improved the bioavailability of antibiotics.

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ER -

Evaluation of FEW ciprofloxacin (CIP) AND norfloxacin (NOR) formulations

Abstract

All Science Journal Classification (ASJC) codes

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