Evaluation of mast cells in oral lichen planus and oral lichenoid reaction.

M. Jose*, A. R. Raghu, N. N. Rao

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Recent attention has been directed towards the role of mast cells in the pathogenesis of oral lichen planus. Mast cells are responsible for trafficking of inflammatory cells into the connective tissue that in turn helps in progression and maintenance of the chronicity of oral lichen planus. In the present study we have evaluated the mast cell count and its cell types using toluidine blue stain, in oral lichen planus and compared it with oral lichenoid reactions. We have observed an increase in mast cell count in both these conditions in comparison to normal mucosa. Also, a significant difference in the types of mast cells in oral lichen planus and oral lichenoid reactions has been noted, possibly suggesting that the role of mast cell is different in these conditions.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalIndian journal of dental research : official publication of Indian Society for Dental Research
Volume12
Issue number3
Publication statusPublished - 07-2001

All Science Journal Classification (ASJC) codes

  • General Dentistry

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