Evaluation of potentiation effect of omega-3 fatty acid on the antidepressant efficacy of escitalopram in albino rats

Amberkar Mohanbabu Vittalrao; Saurabh Agarwal; Meena Kumari Kamalkishore; Basavaraj Poojar

doi:10.13005/bpj/1777

Evaluation of potentiation effect of omega-3 fatty acid on the antidepressant efficacy of escitalopram in albino rats

Amberkar Mohanbabu Vittalrao, Saurabh Agarwal, Meena Kumari Kamalkishore^*, Basavaraj Poojar

^*Corresponding author for this work

Department of Pharmacology, Kasturba Medical College, Manipal

Research output: Contribution to journal › Article › peer-review

Abstract

Depression is a common problem worldwide since the ages.Mostly it is treated with Selective serotonin reuptake inhibitors (SSRI) but they are not effective in each and every patient. Hence other methods for better effective ways to treat depression are needed. Our study thus aims at studying the potentiation effect of omega-3 fatty acid in combination with escitalopram for treatment of depression. Combination therapy also helps to reduce side effects of SSRIs and a lower dose can be used in children and pregnant mothers. Various animal models have been used in this pre-clinical study to study the effect of omega-3 fatty acids. Further clinical studies may be required to validate the results of this study.

Original language	English
Pages (from-to)	1471-1480
Number of pages	10
Journal	Biomedical and Pharmacology Journal
Volume	12
Issue number	3
DOIs	https://doi.org/10.13005/bpj/1777
Publication status	Published - 01-01-2019

All Science Journal Classification (ASJC) codes

Pharmacology

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10.13005/bpj/1777

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Evaluation of potentiation effect of omega-3 fatty acid on the antidepressant efficacy of escitalopram in albino rats

Abstract

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