Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

P. Pragathi; P. V. Bharath Kumar; P. Amar Kumar; M. Ramakanth Reddy; V. Sravani; J. Neeraja; Reeba Mary Eapen; K. Gopalakrishna

doi:10.1007/BF02867428

Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

P. Pragathi
, P. V. Bharath Kumar
, P. Amar Kumar
, M. Ramakanth Reddy
, V. Sravani
, J. Neeraja
, Reeba Mary Eapen
, K. Gopalakrishna^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

Original language	English
Pages (from-to)	195-197
Number of pages	3
Journal	Indian Journal of Clinical Biochemistry
Volume	20
Issue number	2
DOIs	https://doi.org/10.1007/BF02867428
Publication status	Published - 01-01-2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

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10.1007/BF02867428

Cite this

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title = "Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer",

abstract = "Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.",

author = "P. Pragathi and \{Bharath Kumar\}, \{P. V.\} and \{Amar Kumar\}, P. and \{Ramakanth Reddy\}, M. and V. Sravani and J. Neeraja and Eapen, \{Reeba Mary\} and K. Gopalakrishna",

year = "2005",

month = jan,

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doi = "10.1007/BF02867428",

language = "English",

volume = "20",

pages = "195--197",

journal = "Indian Journal of Clinical Biochemistry",

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TY - JOUR

T1 - Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

AU - Pragathi, P.

AU - Bharath Kumar, P. V.

AU - Amar Kumar, P.

AU - Ramakanth Reddy, M.

AU - Sravani, V.

AU - Neeraja, J.

AU - Eapen, Reeba Mary

AU - Gopalakrishna, K.

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

AB - Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.

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U2 - 10.1007/BF02867428

DO - 10.1007/BF02867428

M3 - Article

AN - SCOPUS:24044546491

SN - 0970-1915

VL - 20

SP - 195

EP - 197

JO - Indian Journal of Clinical Biochemistry

JF - Indian Journal of Clinical Biochemistry

IS - 2

ER -

Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

Abstract

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