Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats

B. S. Nayak; B. Vinutha; B. Geetha; B. Sudha

doi:10.1016/j.fitote.2005.08.007

Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats

B. S. Nayak, B. Vinutha, B. Geetha, B. Sudha

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg^{- 1} day^{- 1} for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.

Original language	English
Pages (from-to)	671-675
Number of pages	5
Journal	Fitoterapia
Volume	76
Issue number	7-8
DOIs	https://doi.org/10.1016/j.fitote.2005.08.007
Publication status	Published - 01-12-2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Pharmacology

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10.1016/j.fitote.2005.08.007

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abstract = "The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg- 1 day- 1 for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.",

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AU - Geetha, B.

AU - Sudha, B.

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AB - The ethanolic extract of the flowers of Pentas lanceolata given by oral route to rats at dose of 150 mg kg- 1 day- 1 for 10 days, was studied for its effect on wound healing, using excision wound mode. Significant increase in granulation tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content was observed. Moderate increase in protein content was seen. There was significant reduction in the wound area measurement of the test group as compared to that of controls. The efficacious prohealing action may be due to increased collagen deposition as well as better alignment and maturation.

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Experimental evaluation of Pentas lanceolata flowers for wound healing activity in rats

Abstract

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