Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Muthiah Subramanian; M. S. Harikrishnan; Mukund A. Prabhu; Praveen G. Pai; Saritha S. Shekhar; Kumaraswamy Natarajan

doi:10.1016/j.ipej.2017.07.005

Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Muthiah Subramanian^*
, M. S. Harikrishnan
, Mukund A. Prabhu
, Praveen G. Pai
, Saritha S. Shekhar
, Kumaraswamy Natarajan

^*Corresponding author for this work

Department of Cardiology, Kasturba Medical College, Manipal

Research output: Contribution to journal › Article › peer-review

Abstract

Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology.

Original language	English
Pages (from-to)	176-179
Number of pages	4
Journal	Indian Pacing and Electrophysiology Journal
Volume	17
Issue number	6
DOIs	https://doi.org/10.1016/j.ipej.2017.07.005
Publication status	Published - 11-2017

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1016/j.ipej.2017.07.005

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title = "Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review",

abstract = "Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96\% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology.",

author = "Muthiah Subramanian and Harikrishnan, \{M. S.\} and Prabhu, \{Mukund A.\} and Pai, \{Praveen G.\} and Shekhar, \{Saritha S.\} and Kumaraswamy Natarajan",

note = "Publisher Copyright: {\textcopyright} 2017 Indian Heart Rhythm Society",

year = "2017",

month = nov,

doi = "10.1016/j.ipej.2017.07.005",

language = "English",

volume = "17",

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journal = "Indian Pacing and Electrophysiology Journal",

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T1 - Familial atrioventricular nodal re-entrant tachycardia

T2 - A case seriers and a systematic review

AU - Subramanian, Muthiah

AU - Harikrishnan, M. S.

AU - Prabhu, Mukund A.

AU - Pai, Praveen G.

AU - Shekhar, Saritha S.

AU - Natarajan, Kumaraswamy

PY - 2017/11

Y1 - 2017/11

N2 - Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology.

AB - Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology.

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DO - 10.1016/j.ipej.2017.07.005

M3 - Article

AN - SCOPUS:85028462206

SN - 0972-6292

VL - 17

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JO - Indian Pacing and Electrophysiology Journal

JF - Indian Pacing and Electrophysiology Journal

IS - 6

ER -

Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Abstract

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