Familial hemophagocytic lymphohistiocytosis in an infant: A case report

Familial Hemophagocytic Lymphohistiocytosis (FHL) is a rare disorder of early childhood more prevalent in consanguineous families. We discuss a case of a 6-month-old female infant presenting with persistent fever, failure to thrive and neurological manifestations. Diagnosis of FHL type 2 was made based on clinical and laboratory parameters and confirmed with genetic testing. Child was started on intravenous corticosteroids under antibiotic coverage along with anti-epileptics and supportive care however the overall clinical condition did not improve and after 6 days of hospital stay the parents requested discharge and was lost to follow-up.