@article{f73c2cfb64b643c9a033b7c16c0862c4,
title = "Fast disintegrating tablets of atenolol by dry granulation method",
abstract = "Atenolol was formulated as fast disintegrating tablet using three superdisintegrants, croscarmellose sodium (Ac-Di-Sol), crospovidone (Polyplasdone XL) and sodium starch glycolate (Explotab). Thirteen formulations were prepared and all had the same amount of ingredients except, the superdisintegrant level. All the superdisintegrants were used at different concentration levels to assess their efficiency and critical concentration level. Physical characteristics, in vitro release characteristics, moisture uptake and stability profile of various formulations were evaluated. Moisture uptake by formulations was studied to reveal any relationship between moisture uptake and disintegration and/or dissolution efficiency. Ac-Di-Sol proved to be the best among the three and showed satisfactory results at 3 kg/cm2 hardness. Formulations were found stable in release profile after 30 d stability studies at room temperature.",
author = "A.A. Shirwaikar and A. Ramesh",
note = "Cited By :21 Export Date: 10 November 2017 CODEN: IJSID Correspondence Address: Shirwaikar, A. A.; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal-576119, India; email: arunshirwaikar@yahoo.co.in References: In; Essentials of Medical Pharmacology (1999) Medical Publishers (P) Ltd, 142, p. 144. , Tripathi, K.D, Eds, 4th Edn, New Delhi; (2001) Pharmacology and Pharmacotherapeutics, p. 226. , Satoskar, R.S, Bhandarkar, S.D. and Ainapure, S.S, Eds, 17th Edn, Popular Prakashan, Mumbai; Corveleyn, S., Remon, J.P., (1997) Int. J. Pharm, 152, p. 216; Sorensen, S.L.P., Sorensen, Biochem., 1909, 22, 352; (1988) Pharmaceutical Preformulation: The Physicochemical Properties of Drug Substances, p. 209. , Wells, J.I, Eds, Ellis Horwood Limited, West Sussex, England; Indian Pharmacopoeia, II, The Controller of Publication, Delhi, 1996, A-80; Banker, G.S., Anderson, N.R., (1987) The theory and practice of industrial pharmacy, p. 297. , Lachman, L, Liberman, H.A. and Kanig, J.L, Eds, 3rd Edn, Varghese Publishing House, Mumbai; The United States Pharmacopeia, The National Formulary, USP 23 NF 18, United States Pharmacopeial Convention, Inc.,Rockville,M.D, 1995, 1792; Horhota, S.T., Burgio, J., Lanski, L., Rhodes, C.T., (1976) J. Pharm. Sci, 65, p. 1747",
year = "2004",
language = "English",
volume = "66",
pages = "422--426",
journal = "Indian Journal of Pharmaceutical Sciences",
issn = "0250-474X",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "4",
}