Abstract
Reaction of active methylene compound with an aldehyde and thiourea under Biginelli conditions reported to yield dihydropyrimidine derivatives in good yield. Herein we report a special case wherein the isolated product was propanenitrile derivative resulting from Knoevenagel condensation of malononitrile with the aldehyde. The structure of the product was confirmed by single crystal X-ray diffraction studies.
| Original language | English |
|---|---|
| Pages (from-to) | 1228-1233 |
| Number of pages | 6 |
| Journal | Research Journal of Pharmaceutical, Biological and Chemical Sciences |
| Volume | 6 |
| Issue number | 3 |
| Publication status | Published - 01-01-2015 |
All Science Journal Classification (ASJC) codes
- General Biochemistry,Genetics and Molecular Biology
- Pharmacology, Toxicology and Pharmaceutics(all)
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