Formulation and evaluation of methotrexate niosomes

N. Udupa, K. S. Chandraprakash, P. Umadevi, G. K. Pillai

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.

Original languageEnglish
Pages (from-to)1331-1342
Number of pages12
JournalDrug Development and Industrial Pharmacy
Issue number11
Publication statusPublished - 01-01-1993

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Organic Chemistry


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