Formulation and evaluation of methotrexate niosomes

N. Udupa; K. S. Chandraprakash; P. Umadevi; G. K. Pillai

doi:10.3109/03639049309074404

Formulation and evaluation of methotrexate niosomes

N. Udupa^*
, K. S. Chandraprakash
, P. Umadevi
, G. K. Pillai

^*Corresponding author for this work

Directorate of Research

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.

Original language	English
Pages (from-to)	1331-1342
Number of pages	12
Journal	Drug Development and Industrial Pharmacy
Volume	19
Issue number	11
DOIs	https://doi.org/10.3109/03639049309074404
Publication status	Published - 01-01-1993

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science
Drug Discovery
Organic Chemistry

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title = "Formulation and evaluation of methotrexate niosomes",

abstract = "Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.",

author = "N. Udupa and Chandraprakash, \{K. S.\} and P. Umadevi and Pillai, \{G. K.\}",

year = "1993",

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doi = "10.3109/03639049309074404",

language = "English",

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T1 - Formulation and evaluation of methotrexate niosomes

AU - Udupa, N.

AU - Chandraprakash, K. S.

AU - Umadevi, P.

AU - Pillai, G. K.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.

AB - Methotrexate was encapsulated in niosomes prepared using Tweens and Spans. The size distribution, entrapment efficiency, pharmacokinetics and effect on tumour remission of mice transplanted with S-180 Sarcoma were evaluated. Niosomes prepared with Span 60 gave promising results.

UR - https://www.scopus.com/pages/publications/0027154886

UR - https://www.scopus.com/pages/publications/0027154886#tab=citedBy

U2 - 10.3109/03639049309074404

DO - 10.3109/03639049309074404

M3 - Article

AN - SCOPUS:0027154886

SN - 0363-9045

VL - 19

SP - 1331

EP - 1342

JO - Drug Development and Industrial Pharmacy

JF - Drug Development and Industrial Pharmacy

IS - 11

ER -

Formulation and evaluation of methotrexate niosomes

Abstract

All Science Journal Classification (ASJC) codes

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