Full factorial experimental design for development and validation of a RP-HPLC method for estimation of letrozole in nanoformulations

INIS

• performance 100%
• validation 100%
• design 100%
• chromatography 100%
• liquids 100%
• acetonitrile 50%
• ph value 50%
• flow rate 50%
• levels 25%
• solutions 25%
• computer codes 25%
• women 25%
• drugs 25%
• oxygen 25%
• oxidation 25%
• range 25%
• peaks 25%
• concentration 25%
• correlations 25%
• buffers 25%
• recovery 25%
• synthesis 25%
• carbon 18 25%
• precision 25%
• acetates 25%
• mixtures 25%
• hydrolysis 25%
• estrogens 25%
• photolysis 25%

Chemistry

• Procedure 100%
• Liquid Chromatography 100%
• Experimental Design 100%
• Analytical Method 37%
• Column Like Crystal 25%
• Concentration 25%
• Flow Kinetics 25%
• Acetonitrile 25%
• Degradation 25%
• Force 25%
• Correlation 12%
• Factorial Design 12%
• Acetate 12%
• Hydrolysis 12%
• Acid 12%
• Synthesis (Chemical) 12%
• Buffer Solution 12%
• Reaction Temperature 12%
• Aqueous Solution 12%
• Oxidation Reaction 12%
• Alkali 12%
• Mixture 12%
• Mobile Phase Composition 12%
• Chromatography 12%
• Estrogen 12%
• Alkaline Condition 12%
• Block Like Crystal 12%
• Photolysis 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Letrozole 100%