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Genotyping of human adenoviruses circulating in Southwest India

  • C. Akhil
  • , P. G. Suresha
  • , S. Sabeena
  • , M. Hindol
  • , G. Arunkumar*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Adenoviruses are found to be associated with a wide range of diseases in children and adults. There is little data available on the circulating serotypes of Human Adenoviruses (HAdVs) in the southwest region of India. In this study, we explore the molecular epidemiology of HAdVs circulating in southwest India. Twenty-three samples (Adenovirus PCR positive), collected between January 2011 and March 2013, have been typed based on the partial hexon gene sequence and phylogenetic analysis. The commonest serotypes were HAdV-3 and HAdV-2. The other serotypes were HAdV-7, HAdV-1, HAdV-8 and HAdV-40. Respiratory illness was the most common clinical manifestation of HAdV-3, HAdV-2 and HAdV-7 serotypes. HAdV-3, HAdV-7 and HAdV-8 were found to cause conjunctivitis, whereas HAdV-1, HAdV-2 and HAdV-3 caused encephalitis. In conclusion, this study documents the circulating HAdV strains and the epidemiology in southwest India. To the best of our knowledge, this is the first study on the molecular epidemiology of HAdVs in India.

Original languageEnglish
Pages (from-to)266-270
Number of pages5
JournalVirusDisease
Volume27
Issue number3
DOIs
Publication statusPublished - 01-09-2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Infectious Diseases
  • Virology

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