TY - JOUR
T1 - Giant-cell fibroma
T2 - Understanding the nature of the melanin-laden cells
AU - Kulkarni, Spoorti
AU - Chandrashekar, Chetana
AU - Kudva, Ranjani
AU - Radhakrishnan, Raghu
N1 - Publisher Copyright:
© 2017 Journal of Oral and Maxillofacial Pathology | Published by Wolters Kluwer - Medknow.
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Giant-cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant-cell fibroma with stroma strewn with brown pigment-laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Various mechanisms that explain the presence of melanin granules in reactive lesions of giant-cell fibroma is discussed in the present report.
AB - Giant-cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant-cell fibroma with stroma strewn with brown pigment-laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Various mechanisms that explain the presence of melanin granules in reactive lesions of giant-cell fibroma is discussed in the present report.
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U2 - 10.4103/jomfp.JOMFP_209_16
DO - 10.4103/jomfp.JOMFP_209_16
M3 - Article
AN - SCOPUS:85039846384
SN - 0973-029X
VL - 21
SP - 429
EP - 433
JO - Journal of Oral and Maxillofacial Pathology
JF - Journal of Oral and Maxillofacial Pathology
IS - 3
ER -