Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis

Subramanian Kumudhini; Raghavendra Rao; Gauri Salgaonkar; Sricharith Shetty; Sathish Pai

doi:10.4103/0019-5154.190134

Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis

Subramanian Kumudhini
, Raghavendra Rao^*
, Gauri Salgaonkar
, Sricharith Shetty
, Sathish Pai

^*Corresponding author for this work

Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Manipal

Research output: Contribution to journal › Article › peer-review

Abstract

Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

Original language	English
Pages (from-to)	581
Number of pages	1
Journal	Indian Journal of Dermatology
Volume	61
Issue number	5
DOIs	https://doi.org/10.4103/0019-5154.190134
Publication status	Published - 01-09-2016

All Science Journal Classification (ASJC) codes

Dermatology

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abstract = "Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.",

author = "Subramanian Kumudhini and Raghavendra Rao and Gauri Salgaonkar and Sricharith Shetty and Sathish Pai",

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AU - Kumudhini, Subramanian

AU - Rao, Raghavendra

AU - Salgaonkar, Gauri

AU - Shetty, Sricharith

AU - Pai, Sathish

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

AB - Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

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ER -

Granular IgM deposition at basement membrane zone in an infant with diffuse cutaneous mastocytosis

Abstract

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