Granuloma multiforme: an uncommon differential for leprosy

Shibani Bhatia, Shrutakirthi D. Shenoi, Kanthilatha Pai, P. S. Srilatha

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Granuloma multiforme (GM) is a chronic granulomatous skin condition which is clinically characterised by annular lesions mainly over sun-exposed areas and histologically by focal necrobiosis and histiocytic granulomas. Its significance lies in the fact that it can clinically resemble tuberculoid leprosy and hence it can be missed. Here, we report a case of GM from India in a 55-year-old female agriculturist, with multiple asymptomatic large annular rings of papules over the photo-distributed areas. Histopathology helps in confirming the diagnosis and in differentiating it from similar clinical and histologic mimics such as granuloma annulare, tuberculoid leprosy, interstitial granulomatous dermatitis or annular sarcoid. Though a high degree of suspicion is needed to diagnose GM, it should be considered as a differential for various annular conditions.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalTropical Doctor
Issue number1
Publication statusPublished - 01-01-2019

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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