TY - JOUR
T1 - Helicobacter pylori‑Associated Immune Thrombocytopenia
T2 - Diagnostic and Therapeutic Approach
AU - Gosavi, Siddharth
AU - Krishnan, Gokul
AU - Kumar, Vinay
AU - Nityandila, Chinmayee Anand
AU - Rao, Amogh Ananda
AU - Singh, Shiana
AU - Shastry, Barkur Anantha Krishna
N1 - Publisher Copyright:
© 2024 Annals of African Medicine.
PY - 2024
Y1 - 2024
N2 - The relationship between immune thrombocytopenia (ITP) and Helicobacter pylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP. We also elucidated the importance of diagnostic workup and treatment of H. pylori in this article. The mechanisms of H. pylori‑associated ITP have been covered in this article. The factors determining platelet response to H. pylori eradication therapy have been mentioned. It is extremely crucial to be aware that H. pylori is a major causative pathogen for new‑onset ITP as well as chronic ITP. Upper gastrointestinal endoscopic biopsy is the best invasive method for the diagnosis of the same. Further studies need to be conducted across larger, more diverse groups to validate our observation that eradication of H. pylori could aid platelet recovery in ITP.
AB - The relationship between immune thrombocytopenia (ITP) and Helicobacter pylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP. We also elucidated the importance of diagnostic workup and treatment of H. pylori in this article. The mechanisms of H. pylori‑associated ITP have been covered in this article. The factors determining platelet response to H. pylori eradication therapy have been mentioned. It is extremely crucial to be aware that H. pylori is a major causative pathogen for new‑onset ITP as well as chronic ITP. Upper gastrointestinal endoscopic biopsy is the best invasive method for the diagnosis of the same. Further studies need to be conducted across larger, more diverse groups to validate our observation that eradication of H. pylori could aid platelet recovery in ITP.
UR - http://www.scopus.com/inward/record.url?scp=85199250187&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85199250187&partnerID=8YFLogxK
U2 - 10.4103/aam.aam_170_23
DO - 10.4103/aam.aam_170_23
M3 - Review article
C2 - 39034543
AN - SCOPUS:85199250187
SN - 1596-3519
VL - 23
SP - 248
EP - 254
JO - Annals of African Medicine
JF - Annals of African Medicine
IS - 3
ER -