Helicobacter pylori‑Associated Immune Thrombocytopenia: Diagnostic and Therapeutic Approach

Siddharth Gosavi, Gokul Krishnan*, Vinay Kumar, Chinmayee Anand Nityandila, Amogh Ananda Rao, Shiana Singh, Barkur Anantha Krishna Shastry

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The relationship between immune thrombocytopenia (ITP) and Helicobacter pylori infection has largely been an unexplored entity. This review article aims at focusing on the role of H. pylori in secondary ITP. We also elucidated the importance of diagnostic workup and treatment of H. pylori in this article. The mechanisms of H. pylori‑associated ITP have been covered in this article. The factors determining platelet response to H. pylori eradication therapy have been mentioned. It is extremely crucial to be aware that H. pylori is a major causative pathogen for new‑onset ITP as well as chronic ITP. Upper gastrointestinal endoscopic biopsy is the best invasive method for the diagnosis of the same. Further studies need to be conducted across larger, more diverse groups to validate our observation that eradication of H. pylori could aid platelet recovery in ITP.

Original languageEnglish
Pages (from-to)248-254
Number of pages7
JournalAnnals of African Medicine
Volume23
Issue number3
DOIs
Publication statusPublished - 2024

All Science Journal Classification (ASJC) codes

  • General Medicine

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