Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India

Chandana Sai Hari Alladi; Anitha Jagadesh; Suresha G. Prabhu; Govindakarnavar Arunkumar

doi:10.1089/vim.2019.0010

Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India

Chandana Sai Hari Alladi
, Anitha Jagadesh^*
, Suresha G. Prabhu
, Govindakarnavar Arunkumar

^*Corresponding author for this work

Manipal Institute of Virology, Manipal

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.

Original language	English
Pages (from-to)	230-233
Number of pages	4
Journal	Viral Immunology
Volume	32
Issue number	5
DOIs	https://doi.org/10.1089/vim.2019.0010
Publication status	Published - 01-06-2019

All Science Journal Classification (ASJC) codes

Immunology
Molecular Medicine
Virology

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10.1089/vim.2019.0010

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title = "Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India",

abstract = "Influenza viruses are major respiratory pathogens that cause seasonal epidemics and occasional pandemics. Immune response to influenza viruses is majorly targeted against the hemagglutinin antigen. A laboratory-based retrospective cross-sectional study was conducted on 50 acute and 50 follow-up samples to assess the immune response to influenza A(H1N1)pdm09 virus after natural infection and detect the presence of pre-existing antibodies against influenza A(H3N2) and influenza B viruses. Two-fourfold rise in hemagglutination-inhibition (HAI) titer was observed in 100\% of the follow-up samples for influenza A(H1N1)pdm09 virus. No change in HAI titers for influenza A(H3N2) and influenza B viruses was observed.",

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AU - Jagadesh, Anitha

AU - Prabhu, Suresha G.

AU - Arunkumar, Govindakarnavar

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Hemagglutination Inhibition Antibody Response Following Influenza A(H1N1)pdm09 Virus Natural Infection: A Cross-Sectional Study from Thirthahalli, Karnataka, India

Abstract

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