|Number of pages||8|
|Journal||Indian Journal of Pharmaceutical Sciences|
|Publication status||Published - 2008|
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Herbal excipients in novel drug delivery systems. / Shirwaikar, A.; Prabhu, S.; Kumar, G.In: Indian Journal of Pharmaceutical Sciences, Vol. 70, No. 4, 2008, p. 415-422.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Herbal excipients in novel drug delivery systems
AU - Shirwaikar, A.
AU - Prabhu, S.
AU - Kumar, G.
N1 - Cited By :32 Export Date: 10 November 2017 CODEN: IJSID Correspondence Address: Shirwaikar, A.; Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal-576 104, India; email: email@example.com Chemicals/CAS: alginic acid, 28961-37-7, 29894-36-8, 9005-32-7, 9005-38-3; chloroquine, 132-73-0, 3545-67-3, 50-63-5, 54-05-7; diltiazem, 33286-22-5, 42399-41-7; ferrous sulfate, 10028-21-4, 10124-49-9, 13463-43-9, 7720-78-7, 7782-63-0; guar gum, 9000-30-0; gum arabic, 9000-01-5; insulin, 9004-10-8; mesalazine, 89-57-6; metoprolol tartrate, 56392-17-7; naproxen, 22204-53-1, 26159-34-2; nicorandil, 65141-46-0; pectin, 9000-69-5; piroxicam, 36322-90-4; rofecoxib, 162011-90-7, 186912-82-3; sotalol, 3930-20-9, 80456-07-1, 959-24-0; starch, 9005-25-8, 9005-84-9; trimetazidine, 13171-25-0, 5011-34-7; xanthan, 11138-66-2; zinc acetate, 557-34-6 References: (1992) Pharm Forum, 18, p. 4387. , USP Subcommittee on excipients; Sinha, V.R., Rachna, K., Polysaccharides in colon specific drug delivery (2001) Int J Pharm, 224, pp. 19-38; Sungthongjeen, S., Pitaksuteepong, T., Somsiri, A., Sriamornsak, P., Studies on pectins as potential hydrogel matrices for controlled release drug delivery (1999) Drug Develop Ind Pharm, 12, pp. 1271-1276; Tho, I., Sande, S.A., Kleinebudde, P., Pectinic acid: A novel excipient for production of pellets by extrusion/spheronisation: Preliminary studies (2002) Eur J Pharm Biopharm, 54, pp. 95-99; Giunchedi, P., Conte, U., Chetoni, P., Saettone, M.F., Pectin microspheres as ophthalmic carriers for piroxicam: Evaluation in vitro and in vivo in albino rabbits (1999) Eur J Pharm Sci, 9, pp. 1-7; Musabayane, C.T., Munjeri, O., Matavire, T.P., Transdermal delivery of chloroquine by amidated pectin hydrogel matrix patch in the rat (2003) Ren Fail, 25, pp. 525-534; Cheng, K., Lim, L.Y., Insulin-loaded calcium pectinate nanoparticles: Effects of pectin molecular weight and formulation pH (2004) Drug Develop Ind Pharm, 30, pp. 359-367; Madziva, H., Kailasapathy, K., Phillips, M., Alginate-pectin microcapsules as a potential for folic acid delivery in foods (2005) J Microencap, 22, pp. 343-351; Liu, L., Chen, G., Fishman, M.L., Hicks, K.B., Pectin gel vehicles for controlled fragrance delivery (2005) Drug Deliv, 12, pp. 149-157; Tonnesen, H.H., Karlssen, J., Alginate in drug delivery systems (2002) Drug Develop Ind Pharm, 28, pp. 621-630; Rajinikanth, P.S., Sankar, C., Mishra, B., Sodium alginate microspheres of metoprolol tartrate for intranasal systemic delivery: Development and evaluation (2003) Drug Deliv, 10, pp. 21-28; Fuchs-Koelwel, B., Koelwel, C., Gopferich, A., Gabler, B., Wiegrebe, E., Lohmann, C.P., Tolerance of a new calcium-alginate-insert for controlled medication therapy of the eye (2004) Ophthalmologe, 101, pp. 496-499; Zeng, W.M., Oral controlled release formulation for highly water-soluble drugs: Drug - sodium alginate - xanthan gum - zinc acetate matrix (2004) Drug Develop Ind Pharm, 30, pp. 491-495; Pandey, R., Ahmad, Z., Sharma, S., Khuller, G.K., Nano-encapsulation of azole antifungals: Potential applications to improve oral drug delivery (2005) Int J Pharm, 301, pp. 268-276; (2002) Text Book of Pharmacognosy, , Trease GE, Evans WC editors, 15th ed. London: Balliere, Tindall;; Te-Wierik, G.H., Eissens, A.C., Bergsma, J., Arends-Scholte, A.W., Bolhuis, G.K., A new generation starch product as excipient in pharmaceutical tablets, III: Parameters affecting controlled drug release from tablets based on high surface area retrograded pregelatinized potato starch (1997) Int J Pharm, 157, pp. 181-187; Larionova, N.V., Ponchel, G., Duchene, D., Larionova, N.I., Biodegradable cross-linked starch/protein microcapsules containing proteinase inhibitor for oral protein administration (1999) Int J Pharm, 189, pp. 171-178; Tuovinen L, Peltonen S, Jarvinen K. Drug release from starch-acetate films. J Control Release 2003;91:345-54; Tuovinen, L., Peltonen, S., Liikola, M., Hotakainen, M., Poso, A., Jarvinen, K., Drug release from starch-acetate microparticles and films with and without incorporated alpha-amylase (2004) Biomaterials, 25, pp. 4355-4362; (2003) Pharmacognosy, pp. 133-166. , Kokate CK, Purohit AP, Gokhale SB, editors, 22 nd ed. 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J Control Release 2003;92:375-82; Munday, D.L., Cox, P.J., Compressed xanthan and karaya gum matrices: Hydration, erosion and drug release mechanisms (2000) Int J Pharm, 203, pp. 179-192; Park, C.R., Munday, D.L., Evaluation of selected polysaccharide excipients in buccoadhesive tablets for sustained release of nicotine (2004) Drug Develop Ind Pharm, 30, pp. 609-617; Gohel, M.C., Amin, A.F., Patel, K.V., Panchal, M.K., Studies in release behavior of diltiazem HCl from matrix tablets containing (hydroxypropyl) methyl cellulose and xanthan gum (2002) Boll Chim Farm, 141, pp. 21-28; Santos, H., Veiga, F., Pina, M.E., Sousa, J.J., Compaction compression and drug release properties of diclofenac sodium and ibuprofen pellets comprising xanthan gum as a sustained release agent (2005) Int J Pharm, 295, pp. 15-27; Vendruscolo, C.W., Andreazza, I.F., Ganter, J.L., Ferrero, C., Bresolin, T.M., Xanthan and galactomannan (from M. scabrella) matrix tablets for oral controlled delivery of theophylline (2005) Int J Pharm, 296, pp. 1-11; Siahi, M.R., Barzegar-Jalali, M., Monaijemzadeh, F., Ghaffari, F., Azarmi, S., Design and evaluation of 1- and 3-layer matrices of verapamil hydrochloride for sustaining its release (2005) AAPSPharmSciTech, 6, pp. E626-E632; Krishnaiah, Y.S., Bhaskar, P., Studies on the transdermal delivery of nimodipine from a menthol-based TTS in human volunteers (2004) Curr Drug Deliv, 1, pp. 93-102; Yong, C.S., Yang, C.H., Rhee, J.D., Lee, B.J., Kim, D.C., Kim, D.D., Enhanced rectal bioavailability of ibuprofen in rats by poloxamer 188 and menthol (2004) Int J Pharm, 269, pp. 169-176; Amnuaikit, C., Ikeuchi, I., Ogawara, K., Higaki, K., Kimura, T., Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use (2005) Int J Pharm, 289, pp. 167-178; Krishnaiah, Y.S., Chandrasekhar, D.V., Rama, B., Jayaram, B., Satyanarayana, V., Al-Saidan, S.M., In vivo evaluation of limonene-based transdermal therapeutic system of nicorandil in healthy human volunteers (2005) Skin Pharmacol Physiol, 18, pp. 263-272; Krishnaiah, Y.S., Al-Saidan, S.M., Chandrasekhar, D.V., Satyanarayana, V., Controlled in vivo release of nicorandil from a carvone-based transdermal therapeutic system in human volunteers (2006) Drug Deliv, 13, pp. 69-77; Krishnaiah YS, Al-Saidan SM, Chandrasekhar DV, Satyanarayana V. Bioavailability of nerodilol-based transdermal therapeutic system of nicorandil in human volunteers. J Control Release 2005;106:111-22UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-58149097528&doi=10.4103%2f0250-474X.44587&partnerID=40&md5=a1ffcd6a8375d36a0b8d26c6ff109ae1
PY - 2008
Y1 - 2008
N2 - The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.
AB - The use of natural excipients to deliver the bioactive agents has been hampered by the synthetic materials. However advantages offered by these natural excipients are their being non-toxic, less expensive and freely available. The performance of the excipients partly determines the quality of the medicines. The traditional concept of the excipients as any component other than the active substance has undergone a substantial evolution from an inert and cheap vehicle to an essential constituent of the formulation. Excipients are any component other than the active substance(s) intentionally added to formulation of a dosage form. This article gives an overview of herbal excipients which are used in conventional dosage forms as well as novel drug delivery systems.
U2 - 10.4103/0250-474X.44587
DO - 10.4103/0250-474X.44587
M3 - Article
SN - 0250-474X
VL - 70
SP - 415
EP - 422
JO - Indian Journal of Pharmaceutical Sciences
JF - Indian Journal of Pharmaceutical Sciences
IS - 4