Hesperidin inhibits nitrite-induced methemoglobin formation

M. Sudheer Kumar, K.K. Srinivasan, M.K. Unnikrishnan

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Hesperidin protects hemoglobin from nitrite-induced oxidation to methemoglobin. The protection was not observed when hesperidin was added after the autocatalytic stage of the oxidation of hemoglobin. The ability of hesperidin to scavenge superoxide may be responsible since superoxide is implicated in promoting the autocatalytic stage of oxidation of hemoglobin by nitrite.
Original languageEnglish
Pages (from-to)436-438
Number of pages3
JournalIndian Journal of Pharmaceutical Sciences
Issue number4
Publication statusPublished - 2003


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