High-frequency Repetitive Transcranial Magnetic Stimulation Targeting Left Dorsolateral Prefrontal Cortex for Depression Ameliorates Insomnia yet Triggers Excessive Daytime Sleepiness: A Catch-22 Situation

Jithin T. Joseph, Ashok Jammigumpula, Vidyashree S. Manibettu, Abhiram N. Purohith, Sonia Shenoy, Suma Udupa, Samir Kumar Praharaj*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation technique that is effective and safe for the treatment of depression. We observed improvement in insomnia along with symptoms of depression following high-frequency rTMS over the left dorsolateral prefrontal cortex in a patient with treatment-resistant depression, which progressed to excessive daytime sleepiness during the treatment sessions. Causality assessment suggested a probable association of rTMS with excessive sleepiness. The implications of the effect of rTMS on sleep are discussed.

Original languageEnglish
JournalIndian Journal of Psychological Medicine
DOIs
Publication statusAccepted/In press - 2024

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

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