Highly sensitive C-reactive protein in metabolic syndrome

Sudha Vidyasagar, U. K. Abdul Razak, C. K. Prashanth, D. Muralidhar Varma, K. L. Bairy

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Background: Metabolic syndrome is known to predispose to atherosclerosis. C-reactive protein, a marker of systemic inflammation is significantly associated with the atherosclerotic process. Methods: We prospectively studied the relationship between high-sensitivity C-reactive protein (hs-CRP) with various components of metabolic syndrome in 91 patients with metabolic syndrome at our tertiary care centre in South India. Results: The mean age of patients was 57.5 ± 9.8 years; there were 67 (73.6%) males. On univariate analysis, hs-CRP was found to be significantly increased in patients with diabetes mellitus (p < 0.021) and those with abnormal waist circumference (p<0.003). There was no significant association between hs-CRP and high triglycerides, hypertension, and reduced high density lipoprotein cholesterol. Further, hs-CRP increased significantly with increasing number of components of metabolic syndrome (p< 0.008). Conclusions: Measurement of hs-CRP can be used as a surrogate marker of chronic inflammation in patients with metabolic syndrome.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
JournalJournal, Indian Academy of Clinical Medicine
Issue number3-4
Publication statusPublished - 16-10-2013

All Science Journal Classification (ASJC) codes

  • General Medicine


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